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Psychobiotic Gut-Brain Axis Sleep Support

Bifidobacterium longum

The Psychobiotic for Stress & Sleep
Unlock the connection between your gut and your brain. Bifidobacterium longum is a premier 'psychobiotic' strain shown to support the gut-brain axis. By maintaining a healthy microbiome, this unique strain supports the body's natural response to occasional stress, promotes mental clarity, and encourages restorative sleep patterns.
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Human Strain Profile:

Supports Stress Resilience: Helps the body manage everyday stress via cortisol modulation.

Cognitive Clarity: Supports neural function and mental focus.

Restorative Sleep: Supports natural circadian rhythms without sedation.

Psychobiotic Research: Allen et al. (2016). Bifidobacterium longum 1714 as a translational psychobiotic.

Stress Response: Wang et al. (2019). Bifidobacterium longum improves stress-related behaviors.

VERIFIED OUTCOMES

Real Human Results

Finally found relief

I've tried everything for my gut health. This is the first time I actually felt a difference within a week.

It works scary good

After a month, my bloating is 80% gone and digestive pain is cut in half. It even helped with my brain fog. This is hands down the most effective thing I've found.

What have you got to lose?!

This product actually helps! I can finally leave the house without worry, and my anxiety is so much better. I definitely recommend trying it.

Works Great for Me!

This probiotic has done wonders for my digestion. I feel lighter, more energetic, and less bloated.

This stuff works

Love this stuff! It really works.

Good so far

It doesn't cause any histamine reaction and seems to be of high quality. I'm excited for the long-term gut health benefits.

Seems to be a good product

A good, shelf-stable probiotic that doesn't need refrigeration. The capsules are easy to swallow with no off taste.

High-Quality Packaging

This is a well-presented product with high-quality, professional packaging. It feels premium.

The Psychobiotic Standard

Master Your Stress Response

Bifidobacterium longum is not just a probiotic. It is a 'Psychobiotic'—a unique strain capable of influencing the gut-brain axis to support mental clarity, calm, and resilience.
The Difference

The Zen Master of the Gut

While other strains focus on digestion, B. longum focuses on connection. It colonizes the gut lining to facilitate communication between your microbiome and your brain.
  • Native Strain: One of the first bacteria to colonize humans at birth.
  • Stress Resilience: Helps modulate cortisol levels naturally.
  • Gut-Brain Axis: Supports Vagus nerve signaling.
GENERIC STRAINS (Pass Through) HUMAN STRAIN (Colonizes) Adheres & Persists

Neural Calm from Within

Cortisol Modulation

Helps blunt the physiological response to acute stress.

Signal Clarity

Supports neurotransmitter production (GABA).

Restorative Sleep

Supports natural circadian rhythms without sedation.

PSYCHOBIOTIC ACTION
Ecosystem Health

Diversity = Resilience

Stress causes diversity collapse in the microbiome, leading to a 'leaky' gut and brain fog. B. longum acts as a keystone species, restoring the alpha diversity required for a resilient body and mind.
DIVERSITY STATUS
Resilient
Stressed
Low High Resilience Score Birth Elderly AGE RANGE Balanced & Calm
Low High Resilience Score Birth Elderly AGE RANGE Dysbiosis & Stress
GUT MICROBIOME BRAIN / CNS VAGUS NERVE SIGNALING
Gut-Brain Axis

The Vagus Nerve Connection

The Vagus nerve is the information superhighway connecting your gut and brain. B. longum has been clinically shown to stimulate this pathway, promoting a 'Rest and Digest' state over 'Fight or Flight'. [Image of vagus nerve connecting gut and brain]

Clinical Grade Purity

A high-potency, single strain psychobiotic without fillers.
8B CFU Per Capsule
100% Human Origin
0 Allergens
Common Questions

Understanding Human Strains

Everything you need to know about transitioning from generic probiotics to targeted human strains.
My gut health test showed I have low abundance of this strain. Will this help?

Answer text Yes. Comprehensive stool tests (such as Taxonomy, GI Map, Tiny Health, Viome, Thorne, Zoe, etc.) often reveal "microbial dysbiosis," where keystone species like Bifidobacterium adolescentis or Bifidobacterium longum are missing or critically low. Our Single Strain approach is designed specifically for this use case: it provides a high-potency, targeted inoculation to help re-establish these specific populations.here.

Why choose a single strain over a multi-strain blend?

Most probiotic blends use a "shotgun" approach, combining many weak strains that fight for resources. By focusing on a single, high-potency Human Strain, we eliminate inter-species competition and allow the bacteria to colonize more effectively, delivering a therapeutic dose exactly where your gut needs it.

What is a 'Human Strain' probiotic?

A Human Strain is a bacteria that is native to the human gut, meaning it has evolved alongside us. Unlike soil-based organisms or bovine strains often found in generic probiotics (which pass through transiently), Human Strains like Bifidobacterium adolescentis are capable of adhering to the gut lining and colonizing long-term.

When is the best time to take this?

We recommend taking one capsule 30 minutes before your first meal of the day, or on an empty stomach before bed. This reduces exposure to stomach acid and bile, ensuring the highest survival rate of the bacteria as they travel to your lower intestine.

Does this product need refrigeration?

While our freeze-drying technology ensures shelf stability during shipping and short-term storage, we strongly recommend keeping your bottle in the refrigerator upon arrival. This preserves the maximum CFU count and potency through the expiration date.

Will I experience any side effects?

When introducing a potent Human Strain, some individuals may experience mild bloating or gas for the first few days. This is often a sign that the bacteria are active and restructuring your microbiome. If discomfort persists, try taking the capsule every other day until your system adjusts.

Can I take this while on antibiotics?

Yes, but timing is crucial. Antibiotics kill both good and bad bacteria. To protect your probiotic investment, please take this product at least 2–3 hours away from your antibiotic dose. Continuing use after your antibiotic course finishes is highly recommended to help restore lost diversity.

Should I take this with a prebiotic?

Yes. Human Strains like Bifidobacterium thrive when fed specific fibers. Combining this probiotic with a high-quality prebiotic (such as HMOs, GOS, or resistant starch) creates a "synbiotic" effect, significantly increasing the chances of successful colonization and growth in the gut.

Is this safe for histamine intolerance or MCAS?

Our specific strains of Bifidobacterium are generally considered low-histamine producing and safe for those with histamine sensitivity. Unlike certain Lactobacillus strains which can increase histamine load, Bifido strains often help degrade histamine or remain neutral, making them a safer choice for sensitive individuals.

How long until I see results?

Microbiome modulation is a biological process, not a quick fix. While some users feel digestive relief within days, true colonization and ecosystem shifts typically occur over 4 to 12 weeks of consistent use. We recommend a 3-month protocol for optimal results.

How do delivery formats compare (Capsules vs. Powders/Liquids)?

Format dictates efficacy. The industry is segmented into Capsules (34%), Powder (26%), Liquid (22%), and Tablets (18%).

We chose Capsules (the market leader) specifically for their stability, accurate dosing, and convenience. While powders are popular in infant formulas and liquids are used in specific clinical pediatric settings, capsules offer the best protection for ensuring high-potency human strains survive digestion and colonize effectively.e.

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Have questions about the Human Strain protocol? Our science team is here to help guide your longevity journey.