The "Gut-Brain Axis" is the bidirectional communication highway between your enteric nervous system (gut) and your central nervous system (brain). The primary messengers on this highway are neurotransmitters.
The GABA Connection Gamma-aminobutyric acid (GABA) is the brain's primary "calming" neurotransmitter. Clinical research identifies specific strains of Bifidobacterium as "psychobiotics" because of their unique ability to:
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Synthesize GABA directly in the gut lumen.
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Modulate the Vagus Nerve, sending calming signals to the brain.
The Cortisol Impact Dysbiosis (an imbalance of gut bacteria) is linked to hyperactive HPA-axis activity—meaning higher cortisol (stress hormone) levels. Restoring levels of Bifidobacterium adolescentis has been shown in animal and human models to dampen the stress response.
If you are treating mental wellness, you cannot ignore the microbiome.